Comarison of two ventilatory modes on blood and end tidal carbon dioxide in patients undergoing robotic prostate surgery
Not Applicable
- Conditions
- Health Condition 1: N428- Other specified disorders of prostate
- Registration Number
- CTRI/2020/08/027354
- Lead Sponsor
- Amrita Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age group of 18- 75 years
ASA I, II and III patients
Surgery 2 hrs and greater
BMI 18 -35
Patients undergoing elective robotic prostatic surgery
Exclusion Criteria
BMI > 35
Significant cardiac disease
COPD with moderate impairment
Bronchial asthma
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare arterial to end tidal carbon dioxide pressure gradient between two ventilator strategies (volume controlled versus pressure regulated volume controlled ventilation) in patients undergoing robotic radical prostatectomy surgery in Trendelenburg position at specified time pointsTimepoint: 1.T0 baseline pre-induction on room air <br/ ><br>2.T 1 :10 minutes after creation of pneumoperitoneum in Trendelenburgâ??s position <br/ ><br>3.T 2 : 2 hours into the surgery <br/ ><br>4.T 3: 4 h into surgery <br/ ><br>5.T e : 10 minutes after deflation of the pneumoperitoneum <br/ ><br>
- Secondary Outcome Measures
Name Time Method To assess the impact of ventilator modes on the following <br/ ><br>parameters at specified time points : <br/ ><br>1. Alveolar to arterial oxygen pressure gradient (A-a)DO2 <br/ ><br>2. Peak airway pressure (Paw) <br/ ><br>3. Plateau pressure <br/ ><br>3. Dynamic compliance (Cdyn) <br/ ><br>4. P/F ratio <br/ ><br>Timepoint: 1.T0 baseline pre-induction on room air <br/ ><br>2.T 1 :10 minutes after creation of pneumoperitoneum in Trendelenburgâ??s position <br/ ><br>3.T 2 : 2 hours into the surgery <br/ ><br>4 T 3: 4 h into surgery <br/ ><br>5.T e : 10 minutes after deflation of the pneumoperitoneum <br/ ><br>