Changes in arterial and end tidal carbon dioxide levels before and after fluid resuscitation in septic shock patients admitted in IC
Not Applicable
- Conditions
- Health Condition 1: A419- Sepsis, unspecified organism
- Registration Number
- CTRI/2021/11/038170
- Lead Sponsor
- PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
all patients with age > 18 years admitted in intensive care unit with septic shock.
Exclusion Criteria
patients who refuse to participate in the study and patients having conditions affecting lung permeability like interstitial lung disease, idiopathic pulmonary fibrosis, severe bronchial asthma ,COPD, or cardiovascular conditions like congenital heart disease, valvular heart disease, cardiomyopathy having baseline LVEF < 30% , h/o pulmonary embolism, bronchopleural fistula, extracorporeal life support.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method changes in arterial PCO2 and end- tidal carbon dioxide (EtCO2) pre and post resuscitation in septic shock patientsTimepoint: At 0 hour, 1 hour and 6 hours of resuscitation
- Secondary Outcome Measures
Name Time Method correlation between central venous-arterial PCO2 (â??PCO2) gap and arterial PCO2-EtCO2 (A-E) CO2 gap in all the patientsTimepoint: At 0 hour, 1 hour and 6 hours of resuscitation;correlation between these two gaps in critically ill septicemic patients in the context of extent of fluid requirement, extent of inotrope requirement, extent of organ damage (SOFA score) and ICU mortality <br/ ><br>Timepoint: at the time of admission and discharge/death