Application of Physiological Magnetic Resonance Imaging to Study the Relationship between Subchondral Bone Lesions and Cartilage Degeneration and Intervention Study of Yangxue Rougan Decoction

Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1. Knee joint pain (pain for more than ten days occurred at least twice in the past year);
•2. Imaging standards (K-L grade 0 grade I or grade II, of which K-L grade II only includes osteophyte formation);
•3. MRI indicators: MRI found any 2 of the following 4 items:
•(1) Cartilage morphology WORMS score of 3-6 points;
•(2) Cartilage BLOKS score 2, 3;
•(3) Meniscus BLOKS score 3, 4;
•(4) Bone marrow edema WORMS score 2, 3 points.

•1. Patients with severe primary diseases such as cardiovascular, liver, kidney and hematopoietic system;
•2. There are arthritic diseases such as rheumatoid arthritis and gouty arthritis, and other diseases that affect lower limb function;
•3. People with allergies or allergies to multiple drugs;
•4. Oral, intramuscular, joint injection or soft tissue injection of glucocorticoid within one month;
•5. Long-term use of other drugs that affect the efficacy and safety determination and comprehensive treatment;
•6. Those who are not suitable for MRI examination.

发起方

Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine