ISRCTN91251359已完成不适用
The use of magnetic resonance in non-invasive pancreatic beta-cell imaging: the relation between pancreatic triglyceride accumulation and beta-cell function in human (pre)diabetes
VU University Medical Center, Diabetes Center (The Netherlands)0 个研究点目标入组 40 人开始时间: 2007年8月30日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. Male and female subjects (aged 35-70 years)
- •2. Impaired Fasting Glucose (IFG; plasma glucose > = 6.1 and < 7.0 mmol/l) and/or
- •3. IFG (plasma glucose >= 5.6 and < 7.0 mmol/l) and a family history of Diabetes Mellitus type two (DM2; i.e. first and second degree [i.e. grandparents] relatives) and/or
- •4. Impaired Glucose Tolerance (IGT; 2-hour plasma glucose during 75 g Oral Glucose Tolerance Test [OGTT] 7.8-11.1 mmol/l)
排除标准
- •1. Known diabetes
- •2. History or present liver, exocrine pancreatic or renal disease
- •3. Drug-/alcohol abuse
- •4. Acute cardiovascular disease <3 months prior to screening
- •5. Malignant disease
- •6. Claustrophobia and metal implants or pacemakers (MRI)
- •7. Lack of capacity to understand the aim of the research
- •8. Use of the following:
- •8.1. Glucocorticoids
- •8.2. Cytostatic drugs
- •8.3. Thiazolidinediones
- •8.4. Metformin
- •8.5. Oral contraceptives
- •8.6. Fibrates
- •8.7. Anti epileptic drugs
- •8.8. Centrally acting drugs for neurologic and/or psychiatric indications
研究者
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