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Clinical Trials/ISRCTN91251359
ISRCTN91251359
Completed
N/A

The use of magnetic resonance in non-invasive pancreatic beta-cell imaging: the relation between pancreatic triglyceride accumulation and beta-cell function in human (pre)diabetes

VU University Medical Center, Diabetes Center (The Netherlands)0 sites40 target enrollmentAugust 30, 2007
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Overview

Phase
N/A
Intervention
Not specified
Conditions
Not specified
Sponsor
VU University Medical Center, Diabetes Center (The Netherlands)
Enrollment
40
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
August 30, 2007
End Date
TBD
Last Updated
11 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
VU University Medical Center, Diabetes Center (The Netherlands)

Eligibility Criteria

Inclusion Criteria

  • •1\. Male and female subjects (aged 35\-70 years)
  • •2\. Impaired Fasting Glucose (IFG; plasma glucose \> \= 6\.1 and \< 7\.0 mmol/l) and/or
  • •3\. IFG (plasma glucose \>\= 5\.6 and \< 7\.0 mmol/l) and a family history of Diabetes Mellitus type two (DM2; i.e. first and second degree \[i.e. grandparents] relatives) and/or
  • •4\. Impaired Glucose Tolerance (IGT; 2\-hour plasma glucose during 75 g Oral Glucose Tolerance Test \[OGTT] 7\.8\-11\.1 mmol/l)

Exclusion Criteria

  • •1\. Known diabetes
  • •2\. History or present liver, exocrine pancreatic or renal disease
  • •3\. Drug\-/alcohol abuse
  • •4\. Acute cardiovascular disease \<3 months prior to screening
  • •5\. Malignant disease
  • •6\. Claustrophobia and metal implants or pacemakers (MRI)
  • •7\. Lack of capacity to understand the aim of the research
  • •8\. Use of the following:
  • •8\.1\. Glucocorticoids
  • •8\.2\. Cytostatic drugs

Outcomes

Primary Outcomes

Not specified

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