ISRCTN62033854已完成未知
Magnetic resonance imaging to characterise invasive phenotypes in cerebral gliomas: an observational prospective cohort study
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 145
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. Imaging appearances of a high grade glioma
- •2. Likely to be suitable for radiotherapy (60 Gy) with concomitant and adjuvant temozolomide
- •3. World Health Organization (WHO) performance status (PS) grade 0 or 2
- •4. Aged 18 - 75 years, either sex
- •5. Resection or biopsy (although only those suitable for maximal resection will be considered for the MALTING Trial)
- •Patients for the MALTING Trial will be felt by their consultant neurosurgeon to be suitable for 5-aminolevulinic acid (5-ALA) fluorescence-guided resection with insertion of carmustine wafers.
排除标准
- •1. Unsuitable for a contrast-enhanced MRI (MR unsafe metallic implants, claustrophobia, allergy to gadolinium contrast agent or severe renal impairment)
- •2. Pregnant
- •3. Allergic to aminolevulinic acid
- •4. Suffering from porphyria. Care will be taken if the patient is taking other photosensitising drugs.
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