Cross-Cultural Adaptation and Validation of the Italian Version of the Clinical Assessment of Dysphagia in Neurodegeneration (CADN)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 101
- 试验地点
- 1
- 主要终点
- Clinical Assessment of Dysphagia in Neurodegeneration (CADN)
研究概览
简要总结
The English version of the "Clinical Assessment of Dysphagia in Neurodegeneration" (CADN), represents a rapid and valid clinical assessment tool for dysphagia in neurodegenerative population.
Currently, there is no validated tool in Italian specific for the clinical assessment of dysphagia in neurodegenerative disease with strong psychometric characteristics.
The present study aims to translate and validate the Italian version of CADN in neurodegenerative population. Psychometric properties will be measured.
详细描述
Most of patients with a neurodegenerative disease will develop swallowing impairments (dysphagia) during their disease progression (up to 80%- 100% in Parkinson disease and Amyotrophic Lateral Sclerosis).
Dysphagia is associated with serious clinical complications, particularly regarding loss of life quality, insufficient medication intake, malnutrition, dehydration, and aspiration with subsequent pneumonia, which is the leading cause of death in this population.
Early detection and measurement of dysphagia trough validated and standardized procedures plays a fundamental role in the clinical practice. Clinical assessment by a speech language pathologist (SLP) can provide early identification of dysphagia and its severity and direct clinical decision making.
The English version of the "Clinical Assessment of Dysphagia in Neurodegeneration" (CADN), represents a rapid and valid clinical assessment tool for dysphagia in neurodegenerative population.
Currently, there is no validated tool in Italian specific for the clinical assessment of dysphagia in neurodegenerative disease with strong psychometric characteristics.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of neurodegenerative disease according to the respective consensus criteria
- •>18 years old
- •able to provide informed consent
- •able to follow simple instructions
- •capable of sitting upright for anamnesis and examination for at least 20 min (in chair or wheelchair)
排除标准
- •history of stroke
- •surgery to the head or neck
- •radiotherapy in the last 12 months
- •dysphagia resulting from other known causes
研究组 & 干预措施
Patients with neurodegenerative disease
Patients with neurodegenerative disease
干预措施: Administration of Clinical Assessment of Dysphagia in Neurodegeneration (CADN) (Other)
结局指标
主要结局
Clinical Assessment of Dysphagia in Neurodegeneration (CADN)
时间窗: at 24 hours from enrolment
Clinical assessment tool administrated by a Speech Language Pathologist. The CADN is composed by a clinical case history and a consumption part for a total of 11 item. Severity scores for each item range from 0 (no impairment) to 4 (severe impairment).
Clinical Assessment of Dysphagia in Neurodegeneration (CADN)
时间窗: at the enrolment
Clinical assessment tool administrated by a Speech Language Pathologist. The CADN is composed by a clinical case history and a consumption part for a total of 11 item. Severity scores for each item range from 0 (no impairment) to 4 (severe impairment).
次要结局
- Fiberoptic Endoscopic Evaluation of Swallowing (FEES)(At the enrolment)
研究者
Micol Castellari
Speech-Language Pathologist
Istituti Clinici Scientifici Maugeri SpA