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The Chimerix CMX001 Registry

Terminated
Conditions
Outcomes
Survival Rates
Interventions
Registration Number
NCT02167685
Lead Sponsor
Chimerix
Brief Summary

The prospective observational study is to establish a registry database to evaluate the potential impact of prior treatment with CMX001 on the long-term incidence of specific events, such as outcomes, late CMV and other Double-stranded DNA virus associated events, s well as survival rates in subjects previously enrolled in selected clinical studies of CMX001. Each Registry participant will be followed for a period of approximately 3 years from their enrollment in the Registry.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
550
Inclusion Criteria
  • Have previously completed study CMX001-301 through the Week 24 visit, or participated in another qualifying clinical study with CMX001.
  • Willing and able to understand and provide written informed consent to participate in this observational study
  • Willing and able to participate in all required study activities for the entire duration of the observational study (i.e., agreeable to being contacted at periodic intervals over the course of approximately 10 years following the completion of study CMX001-301 or other qualifying clinical study.
Exclusion Criteria
  • None

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
CMX001CMX001Subjects who have previously participated in CMX001-301 or other CMX001 study.
Primary Outcome Measures
NameTimeMethod
Time to all-cause mortality10 years

evaluate the potential impact of prior treatment with CMX001 on the long-term incidence of specific events, such as the development of new malignancies and late cytomegalovirus (CMV)-associated events, as well as survival rates in subjects previously enrolled in selected clinical studies of CMX001

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (51)

University of California San Diego

🇺🇸

La Jolla, California, United States

St. Vincent Medical Center

🇺🇸

Los Angeles, California, United States

Children's Hospital of LA

🇺🇸

Los Angeles, California, United States

UCLA Medical Center

🇺🇸

Los Angeles, California, United States

Stanford University

🇺🇸

Palo Alto, California, United States

Childrens Hospital of Colorado

🇺🇸

Aurora, Colorado, United States

University of Colorado Denver

🇺🇸

Aurora, Colorado, United States

University of Colorado Hospital/Health Science Center

🇺🇸

Aurora, Colorado, United States

Yale University

🇺🇸

New Haven, Connecticut, United States

Children's National Medical Center

🇺🇸

Washington, District of Columbia, United States

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University of California San Diego
🇺🇸La Jolla, California, United States
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