The Chimerix CMX001 Registry
- Registration Number
- NCT02167685
- Lead Sponsor
- Chimerix
- Brief Summary
The prospective observational study is to establish a registry database to evaluate the potential impact of prior treatment with CMX001 on the long-term incidence of specific events, such as outcomes, late CMV and other Double-stranded DNA virus associated events, s well as survival rates in subjects previously enrolled in selected clinical studies of CMX001. Each Registry participant will be followed for a period of approximately 3 years from their enrollment in the Registry.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 550
- Have previously completed study CMX001-301 through the Week 24 visit, or participated in another qualifying clinical study with CMX001.
- Willing and able to understand and provide written informed consent to participate in this observational study
- Willing and able to participate in all required study activities for the entire duration of the observational study (i.e., agreeable to being contacted at periodic intervals over the course of approximately 10 years following the completion of study CMX001-301 or other qualifying clinical study.
- None
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description CMX001 CMX001 Subjects who have previously participated in CMX001-301 or other CMX001 study.
- Primary Outcome Measures
Name Time Method Time to all-cause mortality 10 years evaluate the potential impact of prior treatment with CMX001 on the long-term incidence of specific events, such as the development of new malignancies and late cytomegalovirus (CMV)-associated events, as well as survival rates in subjects previously enrolled in selected clinical studies of CMX001
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (51)
Children's Hospital of LA
🇺🇸Los Angeles, California, United States
Emory University
🇺🇸Atlanta, Georgia, United States
Winship Cancer Institute Emory University
🇺🇸Atlanta, Georgia, United States
Hackensack
🇺🇸Hackensack, New Jersey, United States
Northwestern University School of Medicine
🇺🇸Chicago, Illinois, United States
Brigham and Women's Hospital/Dana Farber Cancer Institute
🇺🇸Boston, Massachusetts, United States
University of Texas-MD Anderson
🇺🇸Houston, Texas, United States
University of Miami
🇺🇸Miami, Florida, United States
Methodist Healthcare System
🇺🇸San Antonio, Texas, United States
St. Vincent Medical Center
🇺🇸Los Angeles, California, United States
UCLA Medical Center
🇺🇸Los Angeles, California, United States
Washington University School of Medicine
🇺🇸Saint Louis, Missouri, United States
University of Chicago
🇺🇸Chicago, Illinois, United States
St. Judes Children's Hospital
🇺🇸Memphis, Tennessee, United States
University of Iowa Hospitals and Clinics
🇺🇸Iowa City, Iowa, United States
Johns Hopkins University
🇺🇸Baltimore, Maryland, United States
University of Minnesota
🇺🇸Minneapolis, Minnesota, United States
Mt Sinai
🇺🇸New York, New York, United States
Albert Einstein Cancer Center at Montefiore Medical Park
🇺🇸Bronx, New York, United States
Memorial Sloan Kettering Cancer Center
🇺🇸New York, New York, United States
Duke University
🇺🇸Durham, North Carolina, United States
Weil Cornell Medical Center
🇺🇸New York, New York, United States
Oncology Hematology Care, Inc
🇺🇸Cincinnati, Ohio, United States
Baylor Cancer Center
🇺🇸Dallas, Texas, United States
Allegheny-Singer Cancer Institute
🇺🇸Pittsburgh, Pennsylvania, United States
Cincinnati Children's Medical Center
🇺🇸Cincinnati, Ohio, United States
Fred Hutchinson Cancer Research Center
🇺🇸Seattle, Washington, United States
Cliniques Universitaires Saint Luc
🇧🇪Brussels, Belgium
University of Toronto
🇨🇦Toronto, Ontario, Canada
Centre Hospitalier Unversitaire Sart
🇧🇪Liege, Belgium
Hopital Maisonneuve-Rosement
🇨🇦Montreal, Quebec, Canada
Harper University Hospital
🇺🇸Detroit, Michigan, United States
Huntsman Cancer Institute
🇺🇸Salt Lake City, Utah, United States
Henry Ford Hospital
🇺🇸Detroit, Michigan, United States
Intermountain Center for Hematological Malignancies
🇺🇸Salt Lake City, Utah, United States
University of Utah
🇺🇸Salt Lake City, Utah, United States
University of Colorado Hospital/Health Science Center
🇺🇸Aurora, Colorado, United States
Childrens Hospital of Colorado
🇺🇸Aurora, Colorado, United States
University of Colorado Denver
🇺🇸Aurora, Colorado, United States
The Children's Hospital of Philadelphia
🇺🇸Philadelphia, Pennsylvania, United States
University of California San Diego
🇺🇸La Jolla, California, United States
Stanford University
🇺🇸Palo Alto, California, United States
Northside Hospital
🇺🇸Atlanta, Georgia, United States
Children's National Medical Center
🇺🇸Washington, District of Columbia, United States
University of Nebraska
🇺🇸Omaha, Nebraska, United States
Yale University
🇺🇸New Haven, Connecticut, United States
Children's Hospital of New Orleans
🇺🇸New Orleans, Louisiana, United States
University of Michigan Health System
🇺🇸Ann Arbor, Michigan, United States
Children Mercy Hospital and Clinics
🇺🇸Kansas City, Missouri, United States
Wake Forest University Baptist Center
🇺🇸Winston-Salem, North Carolina, United States
Montefiore Medical Center
🇺🇸Bronx, New York, United States