CTIS2024-511053-22-00招募中1 期
PiSCATIN - Simvastatin for the treatment of primary sclerosing cholangitis (PSC) - a randomized double-blind, placebo-controlled multicenter study
Karolinska University Hospital0 个研究点目标入组 560 人开始时间: 2024年2月13日最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 560
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 65+（—）
- 性别
- All
入选标准
- •Patients with a cholangiographically verified PSC and/or liverbiopsy with and without IBD (patients with a present autoimmun hepatit and small duct PSC can be included), Men and women =18 years but =75 years, Patient has given written consent to participate in the study, MR/MRCP within 4 months, Coloscopy within 24 months if the patient has a known IBD, Female of childbearing potential must agree to use a highly efficient method of contraception during the study participation.
排除标准
- •Patients on waiting list for transplantation, Transplanted patients, Patients with severe liver failure = Child B 9 points, Previous varices bleeding secondary to end stage liver disease, Previous cholangiocarcinoma, Patients with secondary sclerosing cholangitis, Patients who have been taking any statin medication during the last 3 months, Intolerance to statins, Pregnancy and breastfeeding
研究者
相似试验
进行中（未招募）
1 期
A trial comparing simvastatin to placebo as a neuronal protective treatment for Parkinson's disease.Parkinson's diseaseMedDRA version: 18.0Level: PTClassification code 10061536Term: Parkinson's diseaseSystem Organ Class: 10029205 - Nervous system disordersMedDRA version: 18.0Level: LLTClassification code 10013113Term: Disease Parkinson'sSystem Organ Class: 10029205 - Nervous system disordersEUCTR2015-000148-40-GBPlymouth Hospitals NHS Trust198
进行中（未招募）
1 期
sing Simvastatin to improve immune responses in older people with pneumoniaEUCTR2012-003343-29-GBniversity of Birmingham56
已完成
不适用
Efficacy of simvastatin in treating patients with traumatic brain injury.Nervous System Diseasestraumatic brain injuryPACTR201708002405365Faculty of medicine El minia university40
已完成
3 期
Simvastatine in the treatment of schizophreniaschizophrenia.schizophreniaIRCT201410021556N65Tehran University of Medical Sciences50
招募中
2 期
Effect of simvastatin in treatment of pachyonychia congenitaIRCT20160320027109N3Shahid Beheshti University of Medical Sciences20