Influence of Intravitreal Aqueous Tamponade on Lens Status and Ocular

Completed

• Conditions: Cataract; Aqueous Tamponade
• Interventions: Procedure: pars plana vitrectomy

• Registration Number: NCT06133660
• Lead Sponsor: Bo Jia

Brief Summary

To observe the effects of vitreous cavity Balanced salt solution (BSS) tamponade on the state of the lens and related parameters of the eye, and whether the changes of the above parameters are correlated with age, gender, diabetes or not, etc., so as to provide references for the diagnosis and treatment of related diseases and scientific research.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-30
• Primary Completion: 2022-10-01
• Study Completion: 2023-03-01
• Status Verified: 2023-11
• Study First Submitted: 2023-11-10
• Study First Submitted QC: 2023-11-10
• Last Update Submitted: 2023-11-10
• Study First Posted: 2023-11-15
• Last Update Posted: 2023-11-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• ① Patients undergoing vitrectomy for diabetic retinopathy, epiretinal membranes, macular hole, retinal detachment, and other diseases;

  • Patients who underwent vitreous silicone oil tamponade and vitreous silicone oil removal due to various causes; ③ Intraoperative BSS was used for fill the vitreous cavity; ④ Before treatment, inform the patient that the clinical data may be used in clinical research, and the patient and his family are informed and sign the informed consent.

Exclusion Criteria

• ① The operation eye was intraocular lens or cataract extraction during operation; ② Suspensory ligament relaxation or rupture, ciliary body detachment or transaction, lens dislocation, endophthalmitis, traumatic cataract;

  • intraoperative lens injury; ④ patients who refused to participate in the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
PPV（pars plana vitrectomy） group	pars plana vitrectomy	-
Silicone oil removal group	pars plana vitrectomy	-

Primary Outcome Measures

Name	Time	Method
lens thickness	1 year
degree of lens opacity	1 year

Secondary Outcome Measures

Name	Time	Method
anterior chamber depth	1 year
axial length	1 year

Trial Locations

Locations (1)

The Second Hospital of Jilin University; 🇨🇳 Changchun, China