Effect of Contrast Medium on Optic Nerve Sheath Diameter
- Conditions
- Optic Nerve Sheath Diameter
- Interventions
- Other: thoracic epidural catheterization
- Registration Number
- NCT04826042
- Lead Sponsor
- Keimyung University Dongsan Medical Center
- Brief Summary
One method of indirect measurement of intracranial pressure is using optic nerve sheath diameter. There is no study whether equal volume of contrast medium injection has any increasing effect of optic nerve sheath diameter.
This study is designed to measure the changes of optic nerve sheath diameter and cerebral oxygenation when equal volume of contrast medium or normal saline was injected in epidural space.
- Detailed Description
Previous study showed that different volume of injections (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia showed siginifiant increase of optic nerve sheath diameter in group of high volumes. Increase of ICP can result in harmful effect including reduced cerebral flow and oxygen saturation. Also, increase of ICP can cause headache, syncope and transient loss of visual acuity. The proven and valid method of measuring ICP indirectly is using optic nerve sheath diameter. This study was designed to examine the changes of optic nerve sheath diameter and cerebral oxygenation when equal volume of contrast medium or normal saline was injected in epidural space.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 42
- lung cancer
- liver cancer
- stomach cancer
- pancreas cancer
- gallbladder
- coagulopathy
- infection
- previous spine fusion at thoracic level
- previous brain lesion
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description normal saline group thoracic epidural catheterization injection of normal saline 6 cc during thoracic epidural catheterization contrast group thoracic epidural catheterization injection of contrast medium 6 cc during thoracic epidural catheterization
- Primary Outcome Measures
Name Time Method optic nerve sheath change during 4 time period Baseline, 10 minutes, 20 minutes, 40 minutes after the completion of the intervention optic nerve sheath change during 4 time period using ultrasound
- Secondary Outcome Measures
Name Time Method cerebral oxygenation change during 4 time period Baseline, 10 minutes, 20 minutes, 40 minutes after the completion of the intervention cerebral oxygenation change during 4 time period using cerebral oximeter
Trial Locations
- Locations (1)
Ji Hee Hong
🇰🇷Daegu, Korea, Republic of