Optic Nerve Sheath Diameter Difference Between Different Injection Volume
- Conditions
- Optic Nerve Sheath Diameter
- Interventions
- Procedure: thoracic epidural catheterization
- Registration Number
- NCT04412109
- Lead Sponsor
- Keimyung University Dongsan Medical Center
- Brief Summary
Valid method of indirect measurement of intracranial pressure is using optic nerve sheath diameter. Different volume of injection is known to affect the degree of increase of intracranial pressure.
This study is desinged to measure the changes of optic nerve sheath diameter and cerebral oxygenation when different volume of normal saline was injected.
- Detailed Description
Previous study showed that different volume of injections (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia showed siginifiant increase of optic nerve sheath diameter in group of high volumes. Increase of ICP can result in harmful effect including reduced cerebral flow and oxygen saturation. Also, increase of ICP can cause headache, syncope and transient loss of visual acuity. The proven and valid method of measuring ICP indirectly is using optic nerve sheath diameter.
This study was designed to examine the changes of optic nerve sheath diameter and cerebral oxygenation when different volume of normal saline was injected.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
- lung cancer
- liver cancer
- stomach cancer
- pancreas cancer
- gallbladder cancer
- coagulopathy
- infection
- previous spine fusion at thoracic level
- previous brain lesion causing increased intracranial pressure
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description injection of low volume of saline thoracic epidural catheterization low volume (5 cc) saline injection during thoracic epidural catheterization injection of high volume of saline thoracic epidural catheterization high volume (20 cc) saline injection during thoracic epidural catheterization injection of intermediate volume of saline thoracic epidural catheterization intermediate volume (10 cc) saline injection during thoracic epidural catheterization
- Primary Outcome Measures
Name Time Method optic nerve sheath change during 4 time period Baseline, 10 minutes, 20 minutes, 40 minutes after the completion of the intervention optic nerve sheath change during 4 time period using ultrasound
- Secondary Outcome Measures
Name Time Method cerebral oxygenation change during 4 time period Baseline, 10 minutes, 20 minutes, 40 minutes after the completion of the intervention cerebral oxygenation change during 4 time period using pressure monitoring kit
Trial Locations
- Locations (1)
Hong ji HEE
🇰🇷Daegu, Korea, Republic of