Effect van MCT inname in gezonde persone
Recruiting
- Conditions
- long-chain fatty acid oxidation disorders, CPT2D, LCHADD, MTPD, VLCADD
- Registration Number
- NL-OMON25246
- Lead Sponsor
- Amsterdam UMC AMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 4
Inclusion Criteria
Healthy male
- Age 18+
Exclusion Criteria
- Hypertriglyceridemia
- Dyslipidaemia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method • Quantification of oxidation rate of MCT, calculated from 13C enrichment of breath CO2<br /><br>• Testing if MCT is elongated by measuring 13C enrichment of C12-22 of plasma FFA, TG, PL, CE, VLDL, LDL and HDL.
- Secondary Outcome Measures
Name Time Method • Minimum duration of fasting that enables us to detect appropriate levels of LCT and free fatty acids in plasma.<br /><br>• Duration of oral MCT administration to accurately measure MCT elongation to plasma LCT.