Rehydration with Intravenous Fluid and Oral Glycerol in Athletes: Effects on Cardiovascular, Hormonal, Thermoregulatory, Metabolic and Performance Variables
- Conditions
- DehydrationOther - Research that is not of generic health relevance and not applicable to specific health categories listed above
- Registration Number
- ACTRN12610001057077
- Lead Sponsor
- niversity of Queensland
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 15
1) male aged 18 – 40 yrs;
2) experienced cyclist;
3) high endurance training status (V•O2max > 55 mL · kg-1 · min-1); and
4) consistently high training volumes for at least the preceding two months
1) a history of current or previous renal, hepatic, cardiovascular, thermoregulatory or endocrine disorders;
2) contraindications to exercising in the heat;
3) any current or chronic health problems or injuries;
4) the use of any diuretic during the preceding four weeks; and
5) having made a blood donation in the preceding three months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in plasma volume (measured using changes to heamoglobin/heamatocrit and Dill and Costal equations) to monitor hydration status.[Pre-dehydration, -1% bodyweight, -2% bodyweight, -3% bodyweight, post-dehydration, post-first hour of rehydration, mid-second hour of rehydration, post-second hour of rehydration, mid-equilibration, post-equilibration and following 15 min, 30 min, 10 km, 20 km, 30 km and 40 km of an exercise performance test.];Exercise performance assessed as time to complete a 40 km time trial.[Following 10 km, 20 km, 30 km and 40 km of a 40 km time trial.]
- Secondary Outcome Measures
Name Time Method