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Rehydration with Intravenous Fluid and Oral Glycerol in Athletes: Effects on Cardiovascular, Hormonal, Thermoregulatory, Metabolic and Performance Variables

Not Applicable
Completed
Conditions
Dehydration
Other - Research that is not of generic health relevance and not applicable to specific health categories listed above
Registration Number
ACTRN12610001057077
Lead Sponsor
niversity of Queensland
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Male
Target Recruitment
15
Inclusion Criteria

1) male aged 18 – 40 yrs;
2) experienced cyclist;
3) high endurance training status (V•O2max > 55 mL · kg-1 · min-1); and
4) consistently high training volumes for at least the preceding two months

Exclusion Criteria

1) a history of current or previous renal, hepatic, cardiovascular, thermoregulatory or endocrine disorders;
2) contraindications to exercising in the heat;
3) any current or chronic health problems or injuries;
4) the use of any diuretic during the preceding four weeks; and
5) having made a blood donation in the preceding three months

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in plasma volume (measured using changes to heamoglobin/heamatocrit and Dill and Costal equations) to monitor hydration status.[Pre-dehydration, -1% bodyweight, -2% bodyweight, -3% bodyweight, post-dehydration, post-first hour of rehydration, mid-second hour of rehydration, post-second hour of rehydration, mid-equilibration, post-equilibration and following 15 min, 30 min, 10 km, 20 km, 30 km and 40 km of an exercise performance test.];Exercise performance assessed as time to complete a 40 km time trial.[Following 10 km, 20 km, 30 km and 40 km of a 40 km time trial.]
Secondary Outcome Measures
NameTimeMethod
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