Using Point-of-Care-Ultrasound (POCUS) to Assess Gastric Contents Among Fasting Pre-operative Patients Taking GLP-1 Agonists.

Completed

• Conditions: Gastroparesis; Delayed Gastric Emptying
• Interventions: Diagnostic Test: gastric ultrasound

• Registration Number: NCT06038734
• Lead Sponsor: University of North Carolina, Chapel Hill

Brief Summary

Given the increased prescription of GLP-1 agonists for both diabetes and obesity management and the implications of the proposed delayed gastric emptying in the setting of an anesthetic, it is critical to determine if patients taking GLP-1 agonists have an increased rate of delayed gastric emptying. The purpose of this prospective gastric ultrasound evaluation of pre-operative patients is to determine the incidence of a full stomach despite a standard pre-operative fasting period.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-09
• Study First Submitted: 2023-09-08
• Study First Submitted QC: 2023-09-08
• Study First Posted: 2023-09-15
• Study Start: 2023-11-10
• Primary Completion: 2024-04-17
• Study Completion: 2024-04-17
• Last Update Submitted: 2024-06-26
• Last Update Posted: 2024-06-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 108

Inclusion Criteria

• GLP-1 agonist use within previous 30 days
• Appropriately fasted per standard guidelines

Exclusion Criteria

• History of gastric surgery / gastric volume reduction
• Critical illness
• Inability to provide informed consent
• <18 years of age

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
GLP-1 agonists	gastric ultrasound	Pre-operative gastric ultrasound to evaluate for retained gastric contents in appropriately fasted patients who are using GLP-1 agonist medications.
Control	gastric ultrasound	Pre-operative gastric ultrasound to evaluate for retained gastric contents in appropriately fasted patients who are not using GLP-1 agonist medications.

Primary Outcome Measures

Name	Time	Method
Retained gastric contents	At time of pre-operative assessment	Presence of retained gastric contents, either liquid or solid

Trial Locations

Locations (1)

University of North Carolina Medical Center; 🇺🇸 Chapel Hill, North Carolina, United States