Therapeutic Hypothermia in Acute Ischemic Stroke (THAIS)

Not Applicable

• Conditions: Ischemic Stroke; Stroke - Ischaemic

• Registration Number: ACTRN12614000071628
• Lead Sponsor: Royal Melbourne Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-01-21
• Last Update Posted: 21 June 2021

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Patients with ischaemic stroke who have undergone successful (TICI 2b/3) endovascular recanalization and are being cared for in intensive care

Informed consent from patient, person responsible or procedural authorization as approved by HREC

Possibility to start hypothermia within 6 hours of stroke onset

Exclusion Criteria

Metallic foreign bodies or severe claustrophobia precluding MRI
Severe co-morbidity or dementia (pre-stroke modified Rankin Scale 4-5)
Clinical diagnosis of pneumonia or other sepsis at baseline
Bradycardia <40bpm at baseline
Skin damage (e.g., inflammation, burns, injuries, ulcerations, hives, rash) at the sites intended to be used for cooling
Contraindication to sedation and intubation
Current participation in another interventional clinical trial

Study & Design

• Study Type: Interventional
• Study Design: Not specified