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Interactive Guidance Therapy With Video Feed-back of Parent and Child With Autism Spectrum Disorder

Not Applicable
Recruiting
Conditions
Autism Spectrum Disorders
Interventions
Behavioral: Baseline sessions TAU
Behavioral: Interactive guidance therapy
Diagnostic Test: Developmental and diagnostic assessments
Behavioral: Developmental assessment -Parental scales
Behavioral: Qualitative analysis
Registration Number
NCT04607616
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Brief Summary

The purpose of this study is to assess the effect of Interactive Guidance Therapy with video feed back (IGT) of parent and child with Autism Spectrum Disorder, under three years of age, using a Single Case Experimental Design (SCED) with multiple baseline across subjects, multicentric, randomized, with multiple replications, blinded scored

Detailed Description

The purpose of this study is to assess the effect of Interactive Guidance Therapy with video feed back (IGT) of parent and child with Autism Spectrum Disorder, under three years of age, using a Single Case Experimental Design.

Early Interventions in Autism Spectrum Disorders (ASD) undergo a major development. The investigators identify three generations of early support: 1) Behavioral studies ; 2) Early Intensive Behavioral Interventions (EIBI), inspired by ABA, focused on targeted ASD disorders 3) Naturalistic Behavioral Developmental Behavioral Interventions (NDBI), more ecological, focused on the child's skills.

Among them, methods of video feedback target parental sensitivity (identification, interpretation, response, contingency and synchrony). The VIPP (Video Interactive Positive Parenting) in children less than one year of age, has shown moderate and long term effects on parent-child interaction. The PACT (Preschool Autism Communication Trial) showed immediate and in the long term effects on the synchronization of the parental response, the child initiation, less importantly on the joint attention, and on the autistic symptoms. The dyadic communication allows for changes in autistic symptoms.

Interactive guidance is a brief video-feedback therapy, based on the analysis of "the here and now" with the parent (s), of videotaped interactions with their child. The objective is to strengthen parental skills, their sensitivity, their ability to decipher and respond to the specific needs of their child.

The interest of IGT in the field of ASD, compared to VIPP and PACT, is to offer a standardized feedback intervention adapted to each dyad, according to the child's and parents skills and difficulties, structured on the "here and now" more than on a predetermined sequence of goals.

The investigators use the Single Case Experimental Design (SCED) with multiple baseline across subjects, multicentric, randomized, with multiple replications, blinded scored.

They expect

* to improve the interactive and communicative basic skills of the child, soon after the ASD diagnosis, by accompanying the parents in the identification and understanding of their child's disorders.

* to propose a method highlighting parental skills, in a collaborative and pleasant way

* To increase the parental alliance in the implementation of a tailored intervention for the child

* To facilitate access to healthcare and reduce the parental wandering in the implementation of intervention

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
24
Inclusion Criteria
  • 18 months to 3 years child at screening
  • Child with a diagnosis of Autism Spectrum Disorder (DSM 5) or pervasive Developmental Disorder (ICD 10)
  • Child with ADI R and ADOS-2 fulfilling the criteria for TSA / PDD at diagnosis
  • Developmental age > 12 months in motility with the Brunet-Lézine test
  • Child with availability of parent most present in daily life, only this parent participating directly in play sessions
  • Signed Informed consent form by both parents
  • Patient affiliated to the health insurance system
Exclusion Criteria
  • Level of language in French of parents insufficient to benefit from the care and fill in the questionnaires
  • Psychiatric parental pathology interfering with interactions with the child, qualitatively assessed by the referring psychiatrist
  • Severe sensory illness of the child (blindness, deafness, degenerative disease)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
3 baselines sessions Treatment As Usual (TAU)Baseline sessions TAUPatients received 3 baseline sessions before interactive guidance therapy
3 baselines sessions Treatment As Usual (TAU)Qualitative analysisPatients received 3 baseline sessions before interactive guidance therapy
5 baselines sessions TAUQualitative analysisPatients received 5 baseline sessions before interactive guidance therapy
5 baselines sessions TAUInteractive guidance therapyPatients received 5 baseline sessions before interactive guidance therapy
7 baselines sessions TAUBaseline sessions TAUPatients received 7 baseline sessions before interactive guidance therapy
3 baselines sessions Treatment As Usual (TAU)Developmental and diagnostic assessmentsPatients received 3 baseline sessions before interactive guidance therapy
3 baselines sessions Treatment As Usual (TAU)Developmental assessment -Parental scalesPatients received 3 baseline sessions before interactive guidance therapy
4 baselines sessions TAUDevelopmental and diagnostic assessmentsPatients received 4 baseline sessions before interactive guidance therapy
5 baselines sessions TAUBaseline sessions TAUPatients received 5 baseline sessions before interactive guidance therapy
5 baselines sessions TAUDevelopmental and diagnostic assessmentsPatients received 5 baseline sessions before interactive guidance therapy
5 baselines sessions TAUDevelopmental assessment -Parental scalesPatients received 5 baseline sessions before interactive guidance therapy
6 baselines sessions TAUDevelopmental and diagnostic assessmentsPatients received 6 baseline sessions before interactive guidance therapy
6 baselines sessions TAUDevelopmental assessment -Parental scalesPatients received 6 baseline sessions before interactive guidance therapy
7 baselines sessions TAUDevelopmental and diagnostic assessmentsPatients received 7 baseline sessions before interactive guidance therapy
7 baselines sessions TAUDevelopmental assessment -Parental scalesPatients received 7 baseline sessions before interactive guidance therapy
8 baselines sessions TAUBaseline sessions TAUPatients received 8 baseline sessions before interactive guidance therapy
4 baselines sessions TAUDevelopmental assessment -Parental scalesPatients received 4 baseline sessions before interactive guidance therapy
4 baselines sessions TAUQualitative analysisPatients received 4 baseline sessions before interactive guidance therapy
3 baselines sessions Treatment As Usual (TAU)Interactive guidance therapyPatients received 3 baseline sessions before interactive guidance therapy
4 baselines sessions TAUInteractive guidance therapyPatients received 4 baseline sessions before interactive guidance therapy
6 baselines sessions TAUBaseline sessions TAUPatients received 6 baseline sessions before interactive guidance therapy
4 baselines sessions TAUBaseline sessions TAUPatients received 4 baseline sessions before interactive guidance therapy
6 baselines sessions TAUInteractive guidance therapyPatients received 6 baseline sessions before interactive guidance therapy
6 baselines sessions TAUQualitative analysisPatients received 6 baseline sessions before interactive guidance therapy
7 baselines sessions TAUInteractive guidance therapyPatients received 7 baseline sessions before interactive guidance therapy
8 baselines sessions TAUDevelopmental and diagnostic assessmentsPatients received 8 baseline sessions before interactive guidance therapy
7 baselines sessions TAUQualitative analysisPatients received 7 baseline sessions before interactive guidance therapy
8 baselines sessions TAUDevelopmental assessment -Parental scalesPatients received 8 baseline sessions before interactive guidance therapy
8 baselines sessions TAUQualitative analysisPatients received 8 baseline sessions before interactive guidance therapy
8 baselines sessions TAUInteractive guidance therapyPatients received 8 baseline sessions before interactive guidance therapy
Primary Outcome Measures
NameTimeMethod
Percentage of time spent in a joint attention situationUp to 15 months

Supported Joint Attention (SUJ) rate is evaluated during the parents-child play-time

Secondary Outcome Measures
NameTimeMethod
Parent-child interactive features / Parental synchronyUp to 15 months

- number of parental responses in synchrony with child

Child development / IFDCUp to 15 months

- IFDC is French adaptation of MacArthur-Bates Communicative Development Inventories evaluated at inclusion visit, guidance session 1, guidance session 10 and guidance session 15

Parent-child interactive features/ joint attentionUp to 15 months

- SUJ and COJ rate initiated by child

Parent-child interactive features / Initiation of communicationUp to 15 months

- Initiation of communication by the child with the parent : in proportion to the child's acts of communication

Autistic Symptoms / CARSUp to 15 months

CARS is Childhood Autism Rating Scale evaluated at inclusion visit, guidance session 1, guidance session 10 and guidance session 15

Parent-child interactive features / DCMA scaleUp to 15 months

- DCMA: dyadic communication measure in autism

Autistic Symptoms ECARUp to 15 months

ECA R is "Evaluation des comportements autistiques Révisée" Scale evaluated at inclusion visit, guidance session 1, guidance session 10 and guidance session 15

Parent-child interactive features / CommunicationUp to 15 months

- Number conversational turns of speech between the child and the parent

Child development / MSELUp to 15 months

- MSEL : is Mullen Scale of Early Learning evaluated at inclusion visit, guidance session 1, guidance session 10 and guidance session 15

Child development / CDIUp to 15 months

- CDI is Child Development Inventory evaluated at inclusion visit, guidance session 1, guidance session 10 and guidance session 15

Autistic Symptoms ADOS-2Up to 15 months

ADOS-2 is Autism diagnostic observation Schedule evaluated at inclusion visit, guidance session 1, guidance session 10 and guidance session 15

Content analysis of guidance session by parentAt 16 months

Targeted interview of parents with the psychologist on the content of guidance session

Adaptive behavior of the childUp to 15 months

Vineland 2 Scale evaluated at inclusion visit, guidance session 1, guidance session 10 and guidance session 15

Autistic Symptoms ADIRUp to 15 months

ADI R is Autism Diagnosis Interview Revised evaluated at inclusion visit, guidance session 1, guidance session 10 and guidance session 15

Change processUp to 15 months

Psychotherapy Process Q-set evaluated at baseline visit 1 and last baseline visit (depend of randomization), guidance session 1 and guidance session 10

Trial Locations

Locations (4)

Hôpital Necker Enfants Malades

🇫🇷

Paris, France

Hôpital Saint Eloi

🇫🇷

Montpellier, France

Hôpital Ville Evrard

🇫🇷

Montreuil, France

Hôpital Pitié Salpétriere

🇫🇷

Paris, France

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