NCT01344694Unknown不适用
Association Between Epicardial Fat, Visceral Fat Accumulation & Cardiovascular Atherosclerosis
Ziv Hospital1 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2011年7月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 110
- 试验地点
- 1
研究概览
简要总结
Background: Visceral fat is increasingly associated with metabolic syndrome and with fatty liver, a condition carrying a high risk of cardiovascular disease. The independent role of epicardial fat deposition in cardiovascular risk remains unclear.
详细描述
Background: Visceral fat is increasingly associated with metabolic syndrome and with fatty liver, a condition carrying a high risk of cardiovascular disease. The independent role of epicardial fat deposition in cardiovascular risk remains unclear. Aim: Evaluate the link between epicardial fat, visceral fat, liver fat accumulation and cardiovascular diseases and carotis atherosclerosis in patients with the major cardiovascular risk factors and with or without metabolic syndrome.
研究设计
- 研究类型
- Observational
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients referred to cardiac CT will be the source of recruitment.
- •patients with excess of visceral fat,
- •30 patients with liver fat accumulation
- •30 sex-age-matched individual (controls) will be enrolled. All patients will undergo a complete family history, personal clinical history, physical examination and blood sampling for biochemical analysis.
- •Informed consent will be obtained from each individual.
排除标准
- •subjects with severe morbid obesity (body mass index [BMI] > 40),
- •recent history of acute illness,
- •clinical history of ischemic heart disease and cerebrovascular disease,
- •typical chest pain,
- •previous coronary artery disease,
- •conventional coronary angiography, percutaneous interventions, coronary by pass grafting, renal failure, cancer patients,
- •subjects who take drugs that induces hepatic steatosis ( corticosteroids, estrogens, methotrexate, amiodarone and others)
研究者
研究点 (1)
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