Avastin as an Adjunct to Diode Laser in the Treatment of Neovascular Glaucoma
Phase 2
Completed
- Conditions
- Neovascular Glaucoma
- Interventions
- Procedure: Diode laser cyclophotocoagulation enhanced by intravitreal injection of Avastin
- Registration Number
- NCT01051583
- Lead Sponsor
- Cairo University
- Brief Summary
Assess the efficacy of Avastin as an adjunct to Diode Laser cyclophotocoagulation in the treatment of Neovascular Glaucoma.
- Detailed Description
Design: Prospective, comparative interventional case series. Method: Patients were randomly assigned into Group A which were treated with Diode laser cyclophotocoagulation alone, whereas group B received intravitreal Avastin (One milligram = 0.04mL of 25 mg/mL) in conjunction with the Diode Laser. The preoperative data included etiology, mean age; follow up period, and a full ophthalmological examination with emphasis on mean IOP, iris neovascularization, pain and corneal edema.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
- Neovascular absolute glaucoma
- Painful blind eyes
Exclusion Criteria
- Neovascular glaucoma with useful vision or potential for useful vision
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Avastin , diode laser cyclophotcoagulation Diode laser cyclophotocoagulation enhanced by intravitreal injection of Avastin Intravitreal Avastin injection in conjunction with diode laser cyclophotocoagulation Diode Laser cyclophotocoagulation Diode laser cyclophotocoagulation enhanced by intravitreal injection of Avastin Diode laser cyclophotocoagulation to control intraocular pressure
- Primary Outcome Measures
Name Time Method Disappearance of iris neovessels 2 weeks
- Secondary Outcome Measures
Name Time Method Intra ocular pressure 4 weeks
Trial Locations
- Locations (1)
Kasr El-Ainy hospital, Cairo university,ophthalmology departement
🇪🇬Cairo, Egypt