Accuracy of glioma imaging
Recruiting
- Conditions
- EN: gliomaNL: glioom
- Registration Number
- NL-OMON29302
- Lead Sponsor
- VU University medical center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Patients of 18 years and older with a MRI interpretation by an expert neuroradiologist of a diffuse infiltrative glioma, and who have an indication, confirmed by the multidisciplinary neuro-oncology tumor-board, for resective surgery.
Exclusion Criteria
Patients who are pregnant or underwent previous brain surgery, cranial irradiation or chemotherapy. Patients with other brain pathology on MRI, such as stroke or multiple sclerosis. Patients with a tumor located infratentorially or in the spinal cord.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Qualitative (high, normal or low signal) and quantitative parameters of MRI and PET for each biopsy site <br /><br>- Qualitative (central glioma, glioma infiltration, normal brain or uninformative) histopathological score of each biopsy site
- Secondary Outcome Measures
Name Time Method - Gene expression of each biopsy site