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Clinical Trials/NCT04153019
NCT04153019
Completed
Not Applicable

PSYCHO-EDUCATIONAL AND REHABILITATIVE INTERVENTION FOR THE ONCOLOGICAL PATIENT WITH CACHEXIA AND HIS CAREGIVER: A FEASIBILITY STUDY

Azienda USL Reggio Emilia - IRCCS1 site in 1 country24 target enrollmentMarch 1, 2019
ConditionsCancer Cachexia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cancer Cachexia
Sponsor
Azienda USL Reggio Emilia - IRCCS
Enrollment
24
Locations
1
Primary Endpoint
Feasibility of the intervention
Status
Completed
Last Updated
10 months ago

Overview

Brief Summary

Half of all cancer patients experience cachexia, with the prevalence rising above 80% in the last weeks of life. The cancer cachexia is a complex relational experience which involves the dyads patients-families. There are no studies on psychosocial interventions on dyads associated with rehabilitative interventions, to support more functional relationships to the management of cancer cachexia.

Primary objective: to evaluate the feasibility of a psycho-educational intervention combined with a physiotherapy intervention on the dyads. Secondary objective: improvement of the Quality of Life of dyads, acceptability of the intervention, adherence to each of the two components.

Methods: non-pharmacological interventional perspective, mixed-method study, addressed to a consecutive 30 cancer patients with cachexia and irreversible cachexia and their caregivers assisted by Hospital Palliative Care Unit.

Registry
clinicaltrials.gov
Start Date
March 1, 2019
End Date
September 30, 2021
Last Updated
10 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Azienda USL Reggio Emilia - IRCCS
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age of 18 years or older
  • Good command of the Italian language
  • Written informed consent
  • Histologically confirmed tumor diagnosis
  • Presence of irreversible cachexia and cachexia (ESPEN3-5 guidelines, MUST calculation)
  • Patients who have identified a caregiver
  • Patients and family members are informed of the diagnosis and the objectives of the therapies and who have reported awareness of the disease phase (evaluated by the palliative doctor).

Exclusion Criteria

  • Patients with prognosis less than three months to enable the rehabilitative intervention
  • Presence of important mental disorder or dementia
  • Severe sensory deficit
  • Presence of diffuse bone metastases that put the patient at risk of fracture during rehabilitation exercise.

Outcomes

Primary Outcomes

Feasibility of the intervention

Time Frame: After 2 months

The proportion of number of dyads who completed the intervention / involved dyads will be evaluated. Compliance will be assessed for each individual component (psycho-social and rehabilitative intervention). The overall intervention will be evaluated feasible if there is compliance greater than or equal to 50 percent to both interventions.

Secondary Outcomes

  • Hand-Grip Strenght Test(After 2 months)
  • 30 seconds sit-to stand test(After 2 months)
  • Ad hoc semi-structured interviews with nurses and physiotherapists(After 2 months)
  • Functional Assessment of Anorexia-Cachexia Therapy (FAACT)(After 1 months)
  • Zarit Burden Interview (ZBI)(After 1 months)
  • Ad-hoc semi-structured interviews aimed at the dyad(After 2 months)

Study Sites (1)

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