Pocket irrigation in peri-implantitis treatment
- Conditions
- Peri-implantitis
- Registration Number
- NL-OMON25224
- Lead Sponsor
- MCG
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 24
The patient is = 18 years of age;
-The patient has at least one endosseous implant in the oral cavity with clinical and radiographical signs of peri-implantitis. Peri-implantitis is defined as progressive loss of marginal bone = 2mm , as compared to the baseline radiograph (after placing the definitive restoration) in combination with bleeding and/or suppuration on probing (Lang and Berglundh 2011);
-The implants have been in function for at least two years;
-The patient is capable of understanding and giving informed consent.
-Medical and general contraindications for the procedures;
-A history of local radiotherapy to the head and neck region;
-Uncontrolled diabetes (HbA1c < 7% or < 53 mmol/mol);
-Smoking
-Use of antibiotics during the last 3 months;
-Long-term use of anti-inflammatory drugs;
-Active periodontitis of the remaining dentition (PPD > 5 mm);
-Incapability of performing basal oral hygiene measures as a result of physical or mental disorders;
-Implants with bone loss exceeding 2/3 of the length of the implant or implants with bone loss beyond the transverse openings in hollow implants;
-Implant mobility;
-Implants at which no position can be identified where proper probing measurements can be performed;
-Previous treatment of the peri-implantitis lesions during the last 3 months (scaling or curettage)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean peri-implant bleeding score (%)
- Secondary Outcome Measures
Name Time Method Full-mouth periodontal bleeding score;<br>- Mean peri-implant and full-mouth periodontal suppuration on probing score (%);<br>- Mean peri-implant and full-mouth periodontal probing pocket depth; <br>- Mean peri-implant and full-mouth periodontal plaque score (%);<br>- Marginal soft tissue recession (REC);<br>- Microbiological composition of the peri-implant and periodontal area;<br>- Need for additional surgery at teeth and implants;<br>- Implant failure, defined as implant mobility of previously clinically osseointegrated implants and removal of non-mobile implants because of progressive marginal bone loss or infection;<br>- Tooth loss, defined as removal of teeth because of progressive marginal bone loss or infection;<br>- Complications and adverse events.<br>- Patient satisfaction<br>