Effects of Plant Extracts on Semen Quality
Not Applicable
Completed
- Conditions
- Poor Semen Quality
- Interventions
- Dietary Supplement: PlaceboDietary Supplement: Extracts of Punica granatum and Alpinia galanga
- Registration Number
- NCT01357044
- Lead Sponsor
- Horsens Hospital
- Brief Summary
this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality. The investigators hypothesize that these plant extracts will improve semen quality.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 70
Inclusion Criteria
- Reduced semen quality
Exclusion Criteria
- Total count of motile sperm less than 1 million sperm/ejaculate or more than 200 million sperm/ejaculate
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo - Plant extracts Extracts of Punica granatum and Alpinia galanga -
- Primary Outcome Measures
Name Time Method Count of motile sperm per ejaculate Each participant is given plant extract for three months with flanking semen analyses.
- Secondary Outcome Measures
Name Time Method Morphology: percentage of morphologically abnormal sperm in the ejaculate Each participant is given plant extract for three months with flanking semen analyses. If we find an increase in the primary outcome measure in data from participants receiving plant extracts and not in those receiving placebo tablets, we wish to further investigate whether sperm morphology also improves when consuming the plant extracts, e.g. whether the percentage of abnormal sperm in an ejaculate decreases in the group of participants receiving the active plant extracts
Trial Locations
- Locations (1)
Laboratory of Reproductive Biology
🇩🇰Horsens, Denmark