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临床试验/CTRI/2021/11/037907
CTRI/2021/11/037907尚未招募2 期

Effectiveness of two novel organic agents on the remineralisation of white spot lesions in primary anterior teeth- A randomised clinical trial

Saveetha Dental College1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2021年11月20日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Remineralisation/ decrease in dimensions of white spot lesions on primary maxillary anterior teeth

研究概览

简要总结

White spot lesions are characterized by subsurface demineralization with an intact surface layer of enamel. These lesions form the foundation of caries and are most often unnoticed or neglected by guardians/ parents of preschool children. These lesions can precipitate a rampant attack of dental caries on short notice in children. This invariably affects the quality of life of children as it may lead to pain and infection. The scope of this study focuses on the early detection of such incipient lesions thereby deflecting its consequences by using preventive agents for remineralization. With the world currently directed towards organic sources and remedies,  natural substances such as plant/fruit extracts as remineralizing agents would be more feasible, safe and acceptable by the parent/ patient.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
3.00 Year(s) 至 6.00 Year(s)(—)
性别
All

入选标准

  • White spot lesions on the labial surface of at least one primary maxillary anterior teeth.

排除标准

  • Cavitated lesions on primary maxillary anterior teeth Developmental enamel alterations Children with systemic diseases Children allergic to any fruits, seeds,nuts Children previously exposed to fluoride.

结局指标

主要结局

Remineralisation/ decrease in dimensions of white spot lesions on primary maxillary anterior teeth

时间窗: 1 and 3 months

次要结局

  • dmft score(1 and 3 months)

研究者

发起方
Saveetha Dental College
申办方类型
Research institution and hospital

研究点 (1)

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