Predictors of Hypofibrinogenemia in Severe Trauma

Completed

• Conditions: Severe Trauma

• Registration Number: NCT03020849
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

In this retrospective and prospective study, the aim is to determine a score for predicting a fibrinogen \<1.5g/L (corresponding to European threshold of Directors recommendations of fibrinogen concentrates)

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Primary Completion: 2015-03
• Study Completion: 2015-03
• Status Verified: 2017-01
• Study First Submitted: 2017-01-10
• Study First Submitted QC: 2017-01-11
• Study First Posted: 2017-01-13
• Last Update Submitted: 2017-07-27
• Last Update Posted: 2017-07-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1038

Inclusion Criteria

• age > 18
• severe trauma

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Exclusion Criteria

• age <18

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rate of fibrinogen in blood sample at hospitalisation	day 0 (at hospitalisation)	This fibrinogen rate is correlated to pre-hospital and admission clinical parameters (trauma type, physiologic status, treatments administered, biologic checkup) to predict fibrinogenemia at hospitalisation

Trial Locations

Locations (2)

CHLS, Hospices Civils de Lyon; 🇫🇷 Pierre-Bénite, France

HEH - Hospices Civils de Lyon; 🇫🇷 Lyon, France