External Oblique Intercostal Plane Block Versus Thoracic Paravertebral Block for Post Thoracotomy Pain: A Randomized Non-inferiority Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- External Oblique Intercostal Plane Block
- Sponsor
- Tanta University
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- Total morphine consumption
- Status
- Completed
- Last Updated
- 8 months ago
Overview
Brief Summary
The aim of this study is to compare the effectiveness of analgesia achieved by external oblique intercostal plane block (EOIPB)and thoracic paravertebral block (TPVB) for postoperative pain management in patients undergoing open thoracotomy.
Detailed Description
Acute thoracotomy pain is multifactorial in nature. It involves nociceptive and neuropathic mechanisms originating from somatic and visceral afferents. The main sources of pain are intercostal nerves, the vagus nerve and phrenic nerve in the pleura, the superficial cervical plexus, and the brachial plexus in the ipsilateral shoulder.
Investigators
Mohammed Said ElSharkawy
Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.
Tanta University
Eligibility Criteria
Inclusion Criteria
- •Age ≥ 18 years.
- •Both sexes.
- •American Society of Anesthesiology (ASA) physical status I-III.
- •Scheduled for open thoracotomy
Exclusion Criteria
- •Patients with neurological or intellectual disability.
- •Infection at the injection site.
- •Opioid addiction.
- •Allergic reaction to local anesthetics.
- •Coagulation abnormalities.
- •Drug abuse.
- •Pregnancy.
- •Severe liver and/or renal failure.
- •Uncontrolled hypertension.
- •Severe cardiovascular problems.
Outcomes
Primary Outcomes
Total morphine consumption
Time Frame: 24 hours postoperatively
Rescue analgesia of morphine will be given as 2 mg bolus if the numeric rating scale (NRS) \> 3 to be repeated after 30 min if pain persists until the numeric rating scale \< 4. numeric rating scale will be assessed at 0, 4, 8, 12, 18 and 24h postoperatively.
Secondary Outcomes
- Mean arterial pressure(Till the end of surgery)
- Degree of pain(24 hours postoperatively)
- Heart rate(Till the end of surgery)
- Time to the 1st rescue analgesia(24 hours postoperatively)
- Intraoperative fentanyl consumption(Intraoperative)
- Complications(24 hour postoperatively)