External Oblique Intercostal Block Versus Paravertebral Block for Postoperative Analgesia in Laparoscopic Cholecystectomy Patients

Phase 3

Not yet recruiting

• Conditions: Anesthesia

• Registration Number: NCT06201364
• Lead Sponsor: Assiut University

Brief Summary

To compare external oblique intercostal block versus paravertebral block for post operative analgesia in patients undergoing laparoscopic cholecystectomy to decease post operative opioid consumption and use the least dose of local anesthesia.

Detailed Description

Paravertebral Block (PVB) involve injection of local anesthetic in a space immediately lateral to where the spinal nerves emerge from the intervertebral foramina. This technique is being used increasingly for not only intra-operative and post-operative analgesia but also as a sole anesthetic technique for carrying out various procedures. This popularity is mainly due to the ease of the technique and fewer complications.

The external oblique intercostal block is a novel motor- and opioid-sparing technique which blocks both the anterior and lateral cutaneous branches of the thoracoabdominal nerves which innervate the upper abdominal quadrant.

Study Timeline

• Study First Submitted: 2023-12-30
• Study First Submitted QC: 2023-12-30
• Status Verified: 2024-01
• Study First Posted: 2024-01-11
• Last Update Submitted: 2024-01-11
• Last Update Posted: 2024-01-12
• Study Start: 2024-02-01
• Primary Completion: 2025-06-30
• Study Completion: 2025-08-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients between 20-60 years old
• Patients with ASA clinical status I\II
• Patients schedule for laparoscopic cholecystectomy

Exclusion Criteria

• Patients refusal
• Coagulopathy
• Infection at site of injection
• Allergy of local anesthesia
• Sever cardiac disease
• Patients with chest wall deformities

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
total morphine consumption	first 24 hours postoperatively

Secondary Outcome Measures

Name	Time	Method
Time of first rescue analgesia	hours	rescue analgesia will be given in the form of morphine 4 mg when VAS score ≥4
Visual analogue scale (VAS)	at 0.5 ,1,2,4,8,12,24 hours postoperatively	It is a validated subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."