Measuring Geographic Atrophy in AMD Patients Using the Nidek MP-3 Microperimetry Device

Completed

• Conditions: Age-related Macular Degeneration (AMD)
• Interventions: Device: Nidek MP-3

• Registration Number: NCT02445313
• Lead Sponsor: Doheny Image Reading Center

Brief Summary

The investigators would like to know if different imaging devices can improve the quality of images and visualization of imaged tissues. Also, the investigators would like to find out whether these changes are useful in the diagnosis and treatment of eye diseases. Using images of previous participants will allow us to demonstrate the advancement of different technologies, as well be used to allow comparisons between current technologies.

Detailed Description

To test the quality of images from the Nidek MP-3 device and to measure Geographic Atrophy (GA) in patients with Age-related Macular Degeneration (AMD).

Study Timeline

• Study First Submitted: 2015-05-13
• Study First Submitted QC: 2015-05-14
• Study First Posted: 2015-05-15
• Study Start: 2015-06
• Status Verified: 2019-02
• Primary Completion: 2019-02-12
• Study Completion: 2019-02-12
• Last Update Submitted: 2019-02-12
• Last Update Posted: 2019-02-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Normal, healthy participants and patients with AMD

Exclusion Criteria

1. Those suffering from head, neck or other injury which makes them unable to position themselves in head restraint for imaging
2. Participants who are unable to maintain retinal fixation on a specified target
3. Participants unable to achieve sufficient pupil dilation and alignment stability for imaging to take place
4. Patients with media opacity which preclude high quality imaging will be excluded.
5. Exclusion criteria include vulnerable patients; patients under 18, pregnant, economically and educationally disadvantaged, decision impaired, or homeless people. We exclude pregnant women because pregnancy often can alter eye anatomy.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Control	Nidek MP-3	Normal, healthy participants
AMD	Nidek MP-3	Age-related Macular Degeneration participants

Primary Outcome Measures

Name	Time	Method
Geographic Atrophy	1 year

Trial Locations

Locations (1)

Doheny Eye Centers UCLA; 🇺🇸 Pasadena, California, United States