Application of Two Different Synthetic Sequential Media for the Human IVF-Embryo Transfer (IVF-ET) Program

Not Applicable

Completed

• Conditions: Infertility
• Interventions: Other: MRC media; Other: Sydney IVF media

• Registration Number: NCT01356238
• Lead Sponsor: Maria Fertility Hospital

Brief Summary

Quality-controlled commercial media have been used in many in-vitro fertilization (IVF) laboratories. However, commercial media are costly and difficult to compare directly because their exact compositions are not clearly indicated. Although commercially available media have commonly been used in most IVF programs worldwide, there are several advantages to the use of in-house synthetic sequential media at IVF laboratories. First, the results of quality control should be reliable due to a stringent protocol setting-up. Second, any direct supplementations or deletions of specific components are feasible to obtain good quality embryos and high pregnancy rates since those components can be defined. Finally, dependence on commercially available media diminishes so that the laboratory can more easily accommodate unexpected situations or problems, such as a sudden increase in IVF patients. Therefore, the present study was conducted to compare the efficacy of in-house MRC media in the human IVF-embryo transfer (ET) program to that of commercially available media.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-10
• Study Start: 2009-11
• Primary Completion: 2010-09
• Study Completion: 2010-10
• Study First Submitted: 2011-05-17
• Study First Submitted QC: 2011-05-18
• Last Update Submitted: 2011-05-18
• Study First Posted: 2011-05-19
• Last Update Posted: 2011-05-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 360

Inclusion Criteria

• Patients undergoing IVF treatment in our clinic during study period

Exclusion Criteria

• Females older than 40 years
• Patients showed fertilization failure
• Patients with less than two 2PN embryos

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
MRC media	MRC media	Use MRC media in the human IVF-ET program
Sydney IVF media	Sydney IVF media	Use Sydney IVF media in the human IVF-ET program

Primary Outcome Measures

Name	Time	Method
Embryo Quality	3 Days

Secondary Outcome Measures

Name	Time	Method
Pregnancy and Implantation rates	2 months

Trial Locations

Locations (1)

Maria Fertility Hospital; 🇰🇷 Seoul, Korea, Republic of