Comparison of norepinephrine and dobutamine in patients in cardiogenic shock
- Conditions
- Patients over 18 years of age with cardiogenic shockMedDRA version: 20.0Level: LLTClassification code 10040563Term: Shock cardiogenicSystem Organ Class: 10007541 - Cardiac disordersMedDRA version: 20.0Level: PTClassification code 10007625Term: Cardiogenic shockSystem Organ Class: 10007541 - Cardiac disordersTherapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
- Registration Number
- EUCTR2020-004881-20-IT
- Lead Sponsor
- AZIENDA USL TOSCANA SUD EST Sezione di Arezzo
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- 46
Cardiogenic shock with: systolic systemic blood pressure (PAS) <90 mmHg or mean arterial pressure (MAP) <60 mmHg for at least 30 consecutive minutes and the need for pharmacological support (inotropic and / or vasopressors) to maintain a PAS> 90 mmHg or MAP > 60 mmHg;
Over the age of 18;
Enrollment within 3 hours of the acute event,
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 46
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 46
Pregnancy in progress;
Presence of at least moderate aortic and / or mitral valve disease;
Septic or hypovolemic shock
Mechanical complications of acute myocardial infarction (rupture of the free wall of the heart, interventricular defect, papillary rupture.
Arrhythmic storm, persistent or chronic tachycardic atrial fibrillation.
Patient enrolled in another study
Infusion of inotropes / vasoconstrictors already in place at the time of randomization
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method