Retinal Function in Relation to Long Term Changes in the Glucose Level
- Conditions
- Diabetes Mellitus
- Interventions
- Other: Insulin pump
- Registration Number
- NCT00973401
- Lead Sponsor
- Glostrup University Hospital, Copenhagen
- Brief Summary
The purpose of this study is to measure the amplitude and implicit time of electroretinogram (ERG), darkadaptation and the calibre of retinal vessels before and after optimized medical treatment of diabetic individuals (a lower blood glucose level) over a period of 12 months. Newly diagnosed type 1 and type 2 diabetics as well as dysregulated type 1 and type 2 diabetic individuals will be included. Retinal vessel calibre measurements will be used as an estimation of changes in the retinal perfusion.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Dysregulated type 1 diabetic individuals and newly diagnosed type 1 diabetics. Age >17 < 60 years
Exclusion Criteria
- Test individuals with significant cataract, prior surgery to the eye, diabetic retinopathy, other serious eye disease, hypertension, other serious systemic disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Diabetic individuals Insulin pump -
- Primary Outcome Measures
Name Time Method Changes in amplitude/implicit times, retinal vessel diameter, dark adaptation and OCT 1 week, 1 month, 4 months, 1 year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Glostrup Hospital
🇩🇰Glostrup, Denmark