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Longitudinal Changes in Refractive Error After Primary IOL Implantation Among Children With Congenital Cataract

Completed
Conditions
Cataract
Registration Number
NCT04441268
Lead Sponsor
Sun Yat-sen University
Brief Summary

The purpose of prospective cohort study is to estimate the rate of change in postoperative change after primary IOL implantation among children with congenital cataract(CC) and to explore key factors associated with the rate of change.

Detailed Description

Due to myopic shift, it's difficult to select power of IOL implanted in eye with congenital cataract. The developmental profile of refraction among patient with congenital catarat is has not yet been fully characterized. The investigator recruited a large cohort of Chinese CC children.After primary IOL implatation, routine examinations including retinoscopy were completed. Data were analysed to to estimate the rate of change in postoperative change after primary IOL implantation among children with congenital cataract and to explore key factors associated with the rate of change.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
335
Inclusion Criteria
  • Children with uncomplicated surgeries
  • Children with unilateral/bilateral cataract
Exclusion Criteria
  • Corneal diseases
  • Lens luxation
  • Glaucoma
  • Retinal diseases
  • Nystagmus and nanophthalmos

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The refraction status (presented as spherical equivalent, SE)up to three years after surgery

Refractions were conducted with objective retinoscopy after cycloplegia, and performed by experienced optometrists.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Zhognshan Ophthalmic Center, Sun Yat-sen University

🇨🇳

Guangzhou, Guangdong, China

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