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Cost Effectiveness Of Linezolid In Central America

Withdrawn
Conditions
Ventilator Acquired Pneumonia
Interventions
Registration Number
NCT01040585
Lead Sponsor
Pfizer
Brief Summary

The therapy with Linezolid (LIN) represents better cost-effectiveness vs. Vancomycin (VAN) for the treatment of nosocomial Pneumonia associate to ventilator (VAP).

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Evidence of a legally acceptable representative signed and dated informed consent document indicating that him or her has been informed of all pertinent aspects of the study.
  • Adult (18 years old or older) men and women with confirm diagnosis of VAP treated on ICU with LIN or VAN; on the selected institutions.
Exclusion Criteria
  • Adult men or women with nosocomial pneumonia not associated to a ventilator.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Central America and the CaribbeanLinezolidPanama, Costa Rica, Honduras, El Salvador and Nicaragua
Primary Outcome Measures
NameTimeMethod
The rate of resistance Empirical treatment days before specific therapy. Treatment days with Linezolid. Treatment days with Vancomycin.4 months
Rate of renal failure.4 months
Rate of healing with Linezolid.4 months
Rate of healing with Vancomycin.4 months
Secondary Outcome Measures
NameTimeMethod
Hospitalization days average with VAN and Linezolid.4 months
Variation of prices and values among the different institutions.4 months
The average costs of each intervention.4 months
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