Postnatal Prevalence of Bacteriuria in Women With Catheter Versus no Catheter in Labour: a Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 入组人数
- 638
- 主要终点
- Postpartum Urinary Tract Infection
研究概览
简要总结
Catheterisation is an accepted tool in intrapartum bladder care and indwelling catheters are used routinely before elective caesarean sections. However, urinary catheters are associated with an increased rate of urinary tract infections which can lead to complications including increased maternal morbidity and prolonged hospital stay. A Cochrane Review (2014) concluded that there is insufficient evidence to assess the routine use of indwelling bladder catheters in women undergoing caesarean section. The incidence and causation of catheter-associated infection in this population is unknown. We propose to provide this data, by comparing urine samples from pregnant women before and after their delivery and analysing this against observational catheter use during the delivery. This will be vital in conducting future research into potential change in policy on routine catheterisation. It will also be beneficial to patients as it could reduce the burden of catheterisation by reducing their chance of developing a UTI and by reducing the associated morbidity.
详细描述
Research Question
Is the intrapartum use of a catheter - either intermittent or indwelling - associated with an increased incidence of postnatal bacteriuria when compared with women who are not catheterised?
Method
Pregnant women will be recruited at Gloucestershire Royal Hospital Maternity Department from 37 weeks gestation. Once eligibility is met, they will be asked to provide a mid-stream urine sample which will be tested for microscopy, culture and sensitivity (MC&S). They will be analysed according to their mode of delivery. Their notes will be scrutinised to assess whether or not a catheter was sited during their labour. Postnatally, they will be asked to provide an MSU on day 3 and day 28, which will both be sent for MC&S. A comparative analysis between each MSU will be performed and correlated to whether intrapartum catheterisation was undertaken.
Data Collection & Analysis
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •• Participant is willing and able to give informed consent for participation in the study
- •Intact membranes
- •At least 37 weeks pregnant
排除标准
- •• History of microbiologically-confirmed bacteriuria in preceding 28 days
- •Patients who are in active labour
- •Women who have had either urine-specific or broad-spectrum antibiotics within the last 28 days
结局指标
主要结局
Postpartum Urinary Tract Infection
时间窗: 30 days post delivery
Postpartum urinary tract infection within 30 days of delivery, defined as positive MSU (\>107 cfu/l) with associated symptoms.
次要结局
- Postpartum asymptomatic bacteriuria(30 days post delivery)