Ultra-Low Dose Computed Tomography For Diagnosis And Follow-Up Of Patients With Diffuse Parenchymal Lung Disease (DPLD)
- Conditions
- Diffuse Parenchymal Lung Disease
- Registration Number
- NCT04392726
- Lead Sponsor
- Sheba Medical Center
- Brief Summary
The primary intention of this study is to determine the diagnostic performance of ultra-low-dose CT (ULDCT) in diagnosis and follow-up of diffuse parenchymal lung disease (DPLD). We hypothesize that inspiratory and expiratory chest ULDCT has comparable diagnostic yield to standard dose chest High-resolution computed tomography (HRCT) and utility for follow-up of patients with known DPLD. We will study this hypothesis through the following aims:
1. Determine whether inspiratory and expiratory ULDCT are comparable to HRCT in identifying mosaic attenuation due to air-trapping.
2. Determine whether ULDCT is as good as HRCT for follow-up of patients with established DPLD to identify disease progression.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
- suspected or known DPLD
- referred to DPLD observation
- other lung related diseases
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measure of this study is to determine the diagnostic performance of ULDCT in diagnosis of DPLD. during the procedure/surgery The diagnostic performance will be evaluated according to the biopsy results
The primary outcome measure of this study is to determine the prognostic performance of ULDCT in the follow up of DPLD. during the procedure/surgery The diagnostic performance will be evaluated according to the biopsy results
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Sheba Medical Center
🇮🇱Ramat Gan, Israel