Diagnostic Value of Ultralow-dose Computed Tomography for the Detection of Pulmonary Nodules and Lung Parenchym Alterations Compared to Standard-dose CT
Not Applicable
- Conditions
- Pulmonary EmphysemaMultiple Pulmonary Nodules
- Registration Number
- NCT02468609
- Lead Sponsor
- Cantonal Hospital of St. Gallen
- Brief Summary
To investigate the diagnostic value of ultralow-dose computed tomography in the detection of pulmonary nodules and lung parenchym alterations (e.g. emphysema) compared to standard-dose-CT.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
- planned normal dose-CT by clinical indication at our institution
- obtained informed consent
Exclusion Criteria
- planned lowdose-CT by clinical indication at institution
- no informed consent obtained
- age < 18 years
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Number of pulmonary Nodules detected in the Ultralow-Dose thoracic CT Participants CT-scan will be read out on an average date of 6 weeks after the scan Difference in nodule detectability in Ultralow-Dose-CT compared to Standard-Dose-CT measured using McNemar test
- Secondary Outcome Measures
Name Time Method Patients BMI (Body mass index) Measures assessed at time of read-out on an average date of 6 weeks after the scan Patients Nodule size (mm) Measures assessed at time of read-out on an average date of 6 weeks after the scan
Trial Locations
- Locations (1)
Klinik für Radiologie und Nuklearmedizin
🇨🇭St. Gallen, Switzerland
Klinik für Radiologie und Nuklearmedizin🇨🇭St. Gallen, Switzerland