In-Vitro Maturation of Oocytes From Polycystic Ovarian Patients Undergoing IVF

Not Applicable

Completed

• Conditions: Polycystic Ovarian Syndrome
• Interventions: Other: In-vitro maturation oocytes

• Registration Number: NCT00561808
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

Retrieval of immature oocytes from women with polycystic ovaries, their in-vitro maturation, fertilization and embryo transfer can prevent hormonal treatment that can lead to ovarian hyperstimulation. In addition, it can decrease discomfort and side-effects of routine daily administration of hormones and it can be cost-effective. Thirty healthy women with Polycystic Ovarian Syndrome aged 20-35, with BMI 18-30 kg/msq will be included in the study. Their immature oocytes will be retrieved from small follicles without any hormonal treatment. The oocytes will be fertilized post in-vitro maturation. The developed embryros will be transferred to the patients as in a routine IVF cycle.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2007-11-19
• Study First Submitted QC: 2007-11-19
• Study First Posted: 2007-11-21
• Study Start: 2008-01
• Study Completion: 2009-01
• Status Verified: 2010-03
• Last Update Submitted: 2010-03-08
• Last Update Posted: 2010-03-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

• Healthy women diagnosed with Polycystic Ovarian Syndrome with BMI 18-30 kg/sqm, aged 20-35

Exclusion Criteria

• Every one else

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Observational	In-vitro maturation oocytes	-

Primary Outcome Measures

Name	Time	Method
Maturation rate of oocytes, their fertilization rate, cleavage rate and embryo quality.	one year

Secondary Outcome Measures

Name	Time	Method
Implantation rate and successful delivery.	one year

Trial Locations

Locations (1)

IVF Unit, Hillel Yaffe Medical Center; 🇮🇱 Hadera, Israel