Efficacy and safety of fractional 1064-nm picosecond laser on skin quality
Phase 4
Recruiting
- Conditions
- Patient with mild to moderate wrinklefractional 1064-nm picosecond laser,skin quality
- Registration Number
- TCTR20230516009
- Lead Sponsor
- lasermed co. ltd
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
1. Aged 35-45 years
2. Mild to moderate wrinkle and skin laxity
Exclusion Criteria
1. Patients who are pregnant and lactating
2. Patients had history of anesthesia drug allergy
3. Patients with other skin disease, or having infection at the area of face
4. Immunocompromised patients
5. Patients with hypertrophic scar or keloid
6. Patients with history of Cushing syndrome or Ehlers-Danlos syndromd
7.Patients with cancers or skin cancers
8.Patients with mental disorders
9.Patiens with botox or filler of energy-based deviced within 6 month before joining research
10. patient with keloid or hypertrophic scar
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skin wrinkle and texture Baseline, 4 weeks, 8 weeks, 16 weeks, 28 weeks Antera
- Secondary Outcome Measures
Name Time Method Skin elasticity Baseline, 4 weeks, 8 weeks, 16 weeks, 28 weeks Cutometer,Skin hydration Baseline, 4 weeks, 8 weeks, 16 weeks, 28 weeks corneometer,Melanin and erythema index Baseline, 4 weeks, 8 weeks, 16 weeks, 28 weeks mexameter,Sebum level Baseline, 4 weeks, 8 weeks, 16 weeks, 28 weeks sebumeter,pain score Baseline, 4 weeks, 8 weeks, 16 weeks, 28 weeks Visual Analog Scale,Physician improvement assessment Baseline, 4 weeks, 8 weeks, 16 weeks, 28 weeks Quatile scale,Patient improvement assessment Baseline, 4 weeks, 8 weeks, 16 weeks, 28 weeks Quatile scale,Safety Baseline, 4 weeks, 8 weeks, 16 weeks, 28 weeks Adverse events