Efficacy and safety of fractional 1064-nm picosecond laser on skin quality
Phase 4
Recruiting
- Conditions
- Healthy personfractional 1064-nm picosecond laser,skin quality
- Registration Number
- TCTR20230417008
- Lead Sponsor
- Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
1. Aged from 35 to 45 years old
2. Were diagnosed with mild to moderate wrinkle and skin laxity by dermatologist
Exclusion Criteria
1. Patients who are pregnant, lactating, and postpartum within 1 year
2. Patients who taking oral isotretinoin within 1 year
3. Patients with other skin disease, or having infection at the area of face
4. Immunocompromised patients
5. Patients with hypertrophic scar or keloid
6. Patients with history of Cushing syndrome or Ehlers-Danlos syndromd
7.Patients with cancers or skin cancers
8.Patients with mental disorders
9.Patiens with laser, botox or facial treatment within 6 months
10. patient with herpes simplex infection
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Wrinkle and Texture Baseline, 1, 2,4 7 months Antera
- Secondary Outcome Measures
Name Time Method Skin elasticity Baseline, 1, 2, 4, 7 months Cutometer,Skin hydration Baseline, 1, 2, 4, 7 months corneometer,Melanin and erythema index Baseline, 1, 2, 4, 7 months mexameter,sebum Baseline, 1, 2, 4, 7 months sebumeter,Pain score Baseline, 1, 2, 4, 7 months Visual Analog Scale,Safety Baseline, 1, 2, 4, 7 months Adverse events,Patient evaluation Baseline, 1, 2, 4, 7 months quatile scale,Doctor evaluation Baseline, 1, 2, 4, 7 months quatile scale