Omitting GnRH-antagonist Dose on the Day of Ovulation Trigger

Phase 2

• Conditions: Pituitary Downregulation
• Interventions: Drug: Omit Citrotide 0.25 dose on the day of triggering of ovulation

• Registration Number: NCT03044756
• Lead Sponsor: Assiut University

Brief Summary

Omitting the GnRH antagonist on the day of the trigger can be cost effective and more convenient to the women. We will study the impact of omitting the antagonist dose in a prospective randomized trial

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01-01
• Status Verified: 2017-02
• Study First Submitted: 2017-02-01
• Study First Submitted QC: 2017-02-06
• Last Update Submitted: 2017-02-06
• Study First Posted: 2017-02-07
• Last Update Posted: 2017-02-07
• Primary Completion: 2017-08-30
• Study Completion: 2017-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• All antagonist cycle ivf who agree to participate

Exclusion Criteria

• expected poor responders.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
-ve arm	Omit Citrotide 0.25 dose on the day of triggering of ovulation	The women who do not receive the GnRH antagonist dose on the day of triggering of ovulation (omitted GnRH antagonist arm)

Primary Outcome Measures

Name	Time	Method
Number of retrieved oocytes	One Month	total number and maturation of the retrieved oocytes

Trial Locations

Locations (1)

Osama Abdalmageed; 🇪🇬 Assiut, Non-US/Non-Canadian, Egypt