Ultrasonographic assessment of diaphragmatic parameters for predicting weaning outcome in patients on mechanical ventilation in intensive care unit setting
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Diagnostic accuracy of diaphragmatic excursion and diaphragmatic thickness fraction by ultrasonography predicting weaning outcome in patients on mechanical ventilation.
研究概览
简要总结
The proposed cohort study will be conducted in the Department of Anaesthesia and Intensive care, Vardhman Mahavir Medical College and Safdarjung Hospital, In 50 patients of age >18years over a period of 18 months. The aim of this study is to ultrasonographically assess diaphragmatic parameters for predicting weaning outcome in patients on mechanical ventilation in the intensive care unit setting. It will assess the diagnostic accuracy of diaphragmatic excursion and diaphragmatic thickness fraction by ultrasonography to predict weaning outcome in patients on mechanical ventilation.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Readiness for weaning from mechanical ventilation as assessed by Recovery from the cause of respiratory failure, Stable haemodynamic status with no requirement for vasopressors, Fully conscious, Glasgow Coma Scale Less than or equal to 14, Fraction of inspired oxygen (Fio2) less than0.5,positive end expiration pressure (PEEP) Less than or equal to 5cm H2O, respiratory rate less than 30, partial pressure of oxygen (PaO2)/FiO2 more than 200.
排除标准
- •Pneumothorax, pleural effusion, collapse, fibrosis
- •History of neuromuscular disease, diaphragmatic palsy, thoracic surgery, any mass or mechanical factor in chest or abdomen 3.Tracheostomy tube in situ
- •Pregnancy, ascites, morbid obesity
- •Surgical dressings over the right lower rib cage.
结局指标
主要结局
Diagnostic accuracy of diaphragmatic excursion and diaphragmatic thickness fraction by ultrasonography predicting weaning outcome in patients on mechanical ventilation.
时间窗: Patient hemodynamically stable, ventilating on T-piece for 1 hour
次要结局
- correlation between diaphragmatic dysfunction with reintubation(within 48 hours of extubation)
- Better predictor of diaphragmatic excursion or diaphragmatic thickness fraction(After extubation)
- compare diaphragmatic rapid shallow breathing index (RSBI) with clinical RSBI(before extubation)