Study of Ultrasonographic assessment of diaphragmatic parameters as predictors of weaning success in the intensive care unit
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Primary outcome is successful weaning defined as no ventilator support for 48 hours post-extubation. Secondary outcomes include diaphragmatic ultrasound parameters (excursion and thickening fraction measured pre-extubation and immediately post-extubation), total ventilation duration, ICU stay, re-intubation incidence, and mortality as recorded.
研究概览
简要总结
This prospective observational study demonstrates that ultrasonographic assessment of diaphragmatic parameters, particularly diaphragmatic excursion combined with the rapid shallow breathing index, serves as a reliable predictor of weaning success in ICU patients. These metrics offer superior predictive value compared to other diaphragmatic measures, such as diaphragmatic thickness fraction and time to peak inspiratory amplitude.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •)subjected to invasive mechanical ventilation for at least 24 hours.
- •suitable for spontaneous breathing trial(SBT) according to ICU protocol by the ICU doctor’s team .
排除标准
- •) age more than 80 years old 2) primary diaphragmatic disease or trauma 3 undergone oesophageal and thoracic surgeries 4) pregnant women 5) electrolyte derangements and other correctable disorders 6)unstable haemodynamics.
结局指标
主要结局
Primary outcome is successful weaning defined as no ventilator support for 48 hours post-extubation. Secondary outcomes include diaphragmatic ultrasound parameters (excursion and thickening fraction measured pre-extubation and immediately post-extubation), total ventilation duration, ICU stay, re-intubation incidence, and mortality as recorded.
时间窗: no ventilator support for 48 hours post-extubation followed up
次要结局
- The secondary outcomes of the study explored the association between diaphragmatic weaning parameters & the Rapid Shallow Breathing Index (RSBI). A significant correlation was found between diaphragmatic excursion & RSBI, while no significant correlation was observed between diaphragmatic thickness fraction or the time to peak inspiratory amplitude of the diaphragm & RSBI.(weaning success at 48 hours post extubation)