The effect of use of probiotic Lactobacillus plantarum in children and adolescents with elevated levels of cholesterol or triglycerides and with nephrotic syndrome

Not Applicable

Recruiting

• Conditions: ephrotic syndrome

• Registration Number: RBR-36byz5
• Lead Sponsor: Patrícia Marques Fortes

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-01-16
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Cases and controls: individuals 2-17 years and 11 months; of both sexes in regular outpatient follow-up for at least 1 year and that have in the last three months:24h proteinuria less than 50 mg / kg / day or 40 mg / m² of body surface area (BSA)Serum Albumin > 2.0 g / dl;
total cholesterol > 170 mg / dl and / or triglyceride levels > 130 mg / dl; preserved renal function (glomerular filtration rate > 60ml / min); in corticoids (prednisone < 1mg / kg / day) and / or cyclosporin 5mg / kg / day; not in use of statins,do not have infectious processes at the time of selection; have not presented clinical or laboratory decompensated SN less than 3 months.

Exclusion Criteria

Individuals with kidney disease from stage III; pregnant women; cancer patients; acquired immunodeficiency syndrome, hypothyroidism, metabolic disease; severe cardiovascular disease; cerebrovascular diseas; symptomatic heart failure; viral or bacterial infectious diseases.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dyslipidemia control

Secondary Outcome Measures

Name	Time	Method
Reduction of inflammatory state