Prevalence of Strokes Secondary to a Reversible Cerebral Vasoconstriction Attributable to Cannabis Consumption in Young Subjects (≤ 45 Years) Hospitalized for an Ischaemic Stroke
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 300
- Locations
- 12
- Primary Endpoint
- Evaluation Cannabis use
Study Overview
Brief Summary
Incidence of strokes has increased these last 20 years in young population. This rise could be linked to alcohol, tobacco or drug use like cannabis. Cannabis has previously been descripted as a potential factor of reversible vasoconstriction. The main objective is to show that an exhaustive assessment of a stroke facing a young person frequently lead to a diagnostic of reversible vasoconstriction due to cannabis use. Evaluation will focus on prevalence of strokes secondary to a reversible vasoconstriction attributable to cannabis in young subjects.
There's a real public healthcare interest in terms of primary and secondary prevention to evaluate the role of cannabis as a risk factor of stroke in young population.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 45 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Subject between 18 and 45 years old
- •Stroke confirmed by medical imaging
- •Written informed consent (subject, nearby or emergency procedure)
- •Subject affiliate to a local healthcare insurance office
- •For female of childbearing potential, an adequate contraceptive measur
Exclusion Criteria
- •Subject with psychiatric disorder, unable to understand the study or cooperate
- •Subject under guardianship or forfeiture of liberty
- •Pregnant or breastfeeding woman
- •Subject in period of exclusion due to another study or still in follow-up of an interventional study
Arms & Interventions
Cannabis User
Intervention: Drug urinal test (Other)
Outcomes
Primary Outcomes
Evaluation Cannabis use
Time Frame: 12 months
Reversible vasoconstriction on medical imaging of intracranial arteries at different moment
Time Frame: 12 months.
medical imaging of intracranial arteries will show new stenoses (topography, number, evolution), and new ischemic or cerebral haemorrhagic lesions
Secondary Outcomes
No secondary outcomes reported