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临床试验/NCT04043559
NCT04043559已完成不适用

Small Cortical Cerebellar Infarctions Are Associated With Patent Foramen Ovale in Young Cryptogenic Stroke Patients

Centre Hospitalier Universitaire de Nīmes1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2019年7月25日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
50
试验地点
1
主要终点
number of infarction lesions

研究概览

简要总结

The investigator retrospectively analyzed consecutive young (<60 years) cryptogenic stroke patients with Patient Foramen Ovale (PFO) recruited between January 2016 and May 2019 in our center, and compared these patients with sex- and age-matched controls with cryptogenic stroke without PFO. Analyzed baseline characteristics: sex, age, cardiovascular risk factors, history of stroke, and cortical/subcortical localization, arterial territory, number of lesions, and lesion size of the acute symptomatic infarction, together with the ROPE score. The presence and the number of acute and chronic SCCI lesions were assessed.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • patients : young (<60 years) adult patients,
  • Patient recruited and registered in our stroke database between January 2016 and May 2016 of our center (Nîmes University Hospital, France),
  • Patients presenting with an acute symptomatic infarction (confirmed by diffusion-weighted MRI) of unknown origin
  • Controls : age-matched controls with cryptogenic stroke without PFO

排除标准

  • 未提供

结局指标

主要结局

number of infarction lesions

时间窗: day 1

Number (increase)

infarction location

时间窗: day 1

anterior, posterior, or mixed anterior-posterior circulation and the cortical/subcortical/corticosubcortical location of infarction

size of subcortical lesion

时间窗: day 1

\< or \>15mm

presence of multiterritorial infarction

时间窗: day 1

mixed anterior-posterior circulation or bilateral anterior circulation

次要结局

未报告次要终点

研究者

发起方
Centre Hospitalier Universitaire de Nīmes
申办方类型
Other
责任方
Sponsor

研究点 (1)

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