To study and compare the injectable route with nasal route of drug delivery in reducing the heart rate and blood pressure during intubation(When a tube is passed through your mouth before surgery when you are unconscious).
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/06/034309
- Lead Sponsor
- Arindam Chatterjee
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
American Society of Anaesthesiologists(ASA) physical status I and II.
Aged between 18 and 60 years.
Undergoing elective surgery under general anaesthesia with endotracheal intubation.
Exclusion Criteria
Known allergy to Dexmedetomidine.
ASA III and IV.
Predicted difficult airway planned for awake intubation.
Emergency surgeries.
Pregnant patients.
Patients on treatment with beta blockers or other rate control drugs, pacemakers.
Patient refusal to participate in the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Haemodynamic parameters like heart rate,blood pressure and oxygen saturation.Timepoint: Baseline,1 minute,2 minute,3 minute,4 minute,5 minute,7 minute,10 minutes post intubation.
- Secondary Outcome Measures
Name Time Method Sedation Score using the Modified Observers Alertness/Sedation Scale. <br/ ><br>Dose sparing effect of Propofol.Timepoint: Sedation score will be assessed 3 minutes prior to induction.