A prospective study to access the efficacy of Clonidine and Fentanyl as adjuvants to Hyperbaric Ropivacaine in infra umbilical surgeries performed under spinal anaesthesia
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Comparing block characteristics in respect to sensory block, motor block and duration of post operative analgesia
研究概览
简要总结
Comparison between intrathecal fentanyl and clonidine as adjuvants to hyperbaric ropivacaine in subarachnoid block for elective lower abdominal surgeries under spinal anaesthesia: A prospective, randomised, double blinded, comparative study.
To compare the duration of motor and sensory block of intrathecal 25mcg fentanyl and intrathecal 30mcg clonidine along with 0.75% hyperbaric ropivacaine.
To compare the post operative analgesia in patients given intrathecal fentanyl and intrathecal clonidine.
To compare the side effects and complications (if any) of the given drug during intraoperative and post operative period.
This is a hospital based, prospective, randomised, double blinded, comparative analytical study on cohort of patients posted for elective lower abdominal surgeries under subarachnoid block in general surgery operation theatre Midnapore Medical College and hospital.
As we are using equipotent dose of fentanyl and clonidine and both increases duration of block and postoperative analgesia we expect both the group receiving fentanyl and clonidine will have a longer duration of block and postoperative analgesia but among both the groups which one will provide longer duration of block and postoperative analgesia will be known after completion of the. study
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Inclusion criteria: 1.ASA grade 1&2
- •Age group of 18-60 years
- •Body mass index between 18.5-24
- •Elective lower abdominal surgeries under spinal anaesthesia.
排除标准
- •Patients with severe cardio- respiratory disease
- •Patients with hepatic and renal disease
- •Patients with neurological disorders
- •Patients with endocrine disorders
- •Subarachnoid block failure
- •Any contraindications for spinal anaesthesia
- •Drug allergy to study drug.
结局指标
主要结局
Comparing block characteristics in respect to sensory block, motor block and duration of post operative analgesia
时间窗: before spinal, after spinal, at 5,10,15,20,25,30,40,50,60,70, 80,90 min after spinal or till completion of surgery and 2hr, 4hr, 10hr, 14hr,18hr, 22hrs, 24 hrs post op
次要结局
- 1. Highest level of sensory block(2. quality of motor block)