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Clinical Trials/NL-OMON47465
NL-OMON47465
Recruiting
Not Applicable

Biomarkers in the blood and skeletal muscle for the improvement of viral myocarditis diagnostics - Diagnostic biomarkers in viral myocarditis

Vrije Universiteit Medisch Centrum0 sites200 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Vrije Universiteit Medisch Centrum
Enrollment
200
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • In the viral myocarditis group patients will be included when they are mentally competent and when they present with suspected viral myocarditis (show flu\-like symptoms combined with acute loss of heart function) and comply to the ESC/ACC position statement for endomyocardial biopsy. In the AMI group (controls) patients will be included when they are mentally competent and present with an acute myocardial infarction. Because viral myocarditis can mimic AMI, we will also include patients who present with infarct\-like complaints, but show non\-occluded epicardial coronary arteries with coronary angiography. Based on subsequent MRI analyses, these patients will later be subdivided into the AMI group (in case of myocardial infarction with non\-occluded coronary arteries (MINOCA)) or the viral myocarditis group.

Exclusion Criteria

  • In the viral myocarditis group the main exclusion criteria are: acute myocardial infarction, prednisolon use or fear of MRI. In the AMI group the main exclusion criteria are to suffer from a viral infection (including HIV). In both groups prednisolon use and mental incompetence is an exclusion cirteria.

Outcomes

Primary Outcomes

Not specified

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