Biomarkers in the blood and skeletal muscle for the improvement of viral myocarditis diagnostics - Diagnostic biomarkers in viral myocarditis

Vrije Universiteit Medisch Centrum0 个研究点目标入组 200 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•In the viral myocarditis group patients will be included when they are mentally competent and when they present with suspected viral myocarditis (show flu-like symptoms combined with acute loss of heart function) and comply to the ESC/ACC position statement for endomyocardial biopsy. In the AMI group (controls) patients will be included when they are mentally competent and present with an acute myocardial infarction. Because viral myocarditis can mimic AMI, we will also include patients who present with infarct-like complaints, but show non-occluded epicardial coronary arteries with coronary angiography. Based on subsequent MRI analyses, these patients will later be subdivided into the AMI group (in case of myocardial infarction with non-occluded coronary arteries (MINOCA)) or the viral myocarditis group.

•In the viral myocarditis group the main exclusion criteria are: acute myocardial infarction, prednisolon use or fear of MRI. In the AMI group the main exclusion criteria are to suffer from a viral infection (including HIV). In both groups prednisolon use and mental incompetence is an exclusion cirteria.

发起方