The possible benefit of prophylactic antibiotic use in patients undergoing unilateral elective inguinal hernia repair with prosthetic material.

Completed

• Conditions: inguinal hernia; surgical site infection; wound infection; Infections and Infestations; Complications of procedures, not elsewhere classified

• Registration Number: ISRCTN85660082
• Lead Sponsor: Diskapi Teaching and Research Hospital (Turkey)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-03-04
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 0

Inclusion Criteria

1. Patients with primary unilateral hernia
2. Patients undergo unilateral primary hernia repair with a previously repaired or leave for interval repair on the contralateral side.
3. Age greater than 18 years, both female and male

Exclusion Criteria

1. Patients undergo simultaneous bilateral hernia repair
2. Patients with newly diagnosed or uncontrolled diabetes mellitus
3. Patients who do not accept the registry and randomisation
4. Incarcerated or strangulated hernias requiring emergency repair
5. Known severe coagulation disorder
6. Patients who use aspirin, clopidogrel (Plavix®) or warfarin (Coumadin®)
7. Recurrent hernias

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Surgical site infection: <br>1. Superficial infection<br>2. Deep infection

Secondary Outcome Measures

Name	Time	Method
Components of the primary outcome: <br>1. Day of infection first recognised<br>2. Microbial culture for identification of the microorganism<br>3. Therapeutic antibiotic regimen according to antibiogram results<br>4. Final result for the wound and prosthetic material