The randomized prospective controlled trial for the detection of dysplasia in patients with ulcerative colitis
Not Applicable
Recruiting
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0001195
- Lead Sponsor
- Yonsei University, Wonju Severance Christian Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
1) Patients with Ulcerative colitis older than 19 years
2) Patients with pancolitis ( duration is more than eight years after diagnosis)
3) Patients with left sided colitis ( duration is more than ten years after diagnosis)
4) Simple clinical colitis activity index <8
5) Truelove and Witts’ Score< mild score
6) patients with written consent
Exclusion Criteria
1) colon cancer history
2) operation of colectomy
3) Boston bowel preparation score is fair or poor
4) Failed insertion
5) abnormality with clotting (PT<50%, APTT>50sec)
6) renal problem
7) patients without written consent
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method detection of dysplasia in patients with ulcerative colitis: Non-chromo random biopsy (NCRB) vs. pan-chromo target biopsy (PCTB) using high-definition (HD) colonoscope
- Secondary Outcome Measures
Name Time Method numbers of biopsies ;Endoscopic withdrawal time (time for both observation and biopsy)